Novel antigen modulation technology that controls T cells to guide the immune system

Many cancers and other diseases are caused, or resist treatment, because T cells can't recognise or target cells correctly.

Our technology modulates antigen presentation, flicking a switch inside cells to alter their appearance to the immune system.​

This approach marks a fundamental shift in how we treat people living with cancers, autoimmune disorders, and infectious diseases.​

We seek to solve immune dysfunction.

Progressing through the clinic​

We uncover novel biology to develop treatments for disease areas with significant unmet need.

Our lead antigen modulator (GWRD5769) delivered strong results during a phase 1/2 trial in oncology, demonstrating proof-of-mechanism and target engagement.​

We have active discovery and development programs across oncology, autoimmunity and virology.

Our team and collaborators are experts in the field of antigen modulation.  

A new therapeutic branch

​We are the first to explore the untapped potential of changing the first step of the T cell signaling cascade - Signal 1 - despite its fundamental importance in T cell activation.​

Changing the treatment paradigm

We're on a mission to deliver a new therapeutic class of treatments to help people living with cancers, autoimmune disorders, and infectious diseases.​

We're looking for talented individuals to join our award-winning team. Do you have what it takes?